Chemical Regulation of Glycosylation Processes

Endothelial cell glycosylation: regulation and modulation of biological processes.

Dual role of melanoma cell adhesion molecule (MCAM)/CD146 in lymphocyte endothelium interaction: MCAM/CD146 promotes rolling via microvilli induction in lymphocyte and is an Synthesis and biological activity of azido analogues of 5,6-dimethylxanthenone-4-acetic acid for use in photoaffinity labeling CTACK a new pro-angiogenic factor for dermal endothelial cells DNA/cationic polymer complex atta...

Regulation of Glycosylation

The Sindbis virus glycoproteins, E l and E2, comprise a useful model system for evaluating the effects of local protein structure on the processing of N-linked oligosaccharides by Golgi enzymes. The conversion of oligomannose to N-acetyllactosamine (complex) oligosaccharides is hindered to different extents at the four glycosylation sites, so that the complex/oligomannose ratio decreases in the...

Thermodynamics of Chemical Processes

Role of protein glycosylation in immune regulation.

Most cell surface and secreted proteins are glycosylated that is, they have one or more oligosaccharide chains covalently attached to specific amino acids. These oligosaccharides usually make up a significant amount of the hydrodynamic mass of the molecules and also have effects on protein conformation, surface expression, stability, circulating half life, activity, and antigenicity. In additio...

Development of Chemical Processes